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Article

Animal models of arrhythmogenic right ventricular cardiomyopathy: what have we learned and where do we go? Insight for therapeutics.

Basic research in cardiology - 1 Sept 2017

Padrón-Barthe Laura, Domínguez Fernando, Garcia-Pavia Pablo, Lara-Pezzi Enrique

Abstract excerpt

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare genetically-determined cardiac heart muscle disorder characterized by fibro-fatty replacement of the myocardium that results in heart failure and sudden cardiac death (SCD), predominantly in young males. The disease is often caused by mutations in genes encoding proteins of the desmosomal complex, with a significant minority caused by mutations in...

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Identifiers

PMID: 28688053
DOI: 10.1007/s00395-017-0640-3

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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