[Familial hypertrophic cardiomyopathy: genes, mutations and animal models. A review].

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease, which may afflict as many as 1 in 500 subjects (0.2%), being probably the most common hereditary cardiovascular disease and the most common cause of sudden cardiac death (SCD). Hypertrophic cardiomyopathy is characterized by the presence of unexplained left ventricular hypertrophy (in absence of hypertension, valvular disease, etc), which is...

Topics

• Actins
• Animals
• Animals, Genetically Modified
• Cardiac Myosins
• Cardiomyopathy, Hypertrophic
• Carrier Proteins
• Connectin
• Disease Models, Animal
• Forecasting
• Humans
• Muscle Proteins