Article
Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2009
Stern Mariana C, Butler Lesley M, Corral Román, Joshi Amit D, Yuan Jian-Min, Koh Woon-Puay, Yu Mimi C
Abstract excerpt
Animal and in vitrostudies support a role for polyunsaturated fatty acids (PUFAs) in colon carcinogenesis; however, the epidemiological evidence is inconclusive. Recently, we investigated their role within the Singapore Chinese Health Study, a population-based cohort of Singapore Chinese men and women. We reported that a high intake of marine n-3 PUFAs was associated with an increased risk of colorectal cancer...
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