Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance.

Circulation research - 6 Aug 2010

van Laake Linda W, Qian Li, Cheng Paul, Huang Yu, Hsiao Edward C, Conklin Bruce R, Srivastava Deepak

Abstract excerpt

RATIONALE: Induced pluripotent stem (iPS) cells can differentiate into multiple cell types, including cardiomyocytes and have tremendous potential for drug discovery and regenerative therapies. However, it is unknown how much variability exists between differentiated lineages from independent iPS cell lines and, specifically, how similar iPS cell-derived cardiomyocytes (iPS-CMs) are to embryonic stem (ES)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryonic Stem Cells
Share to Heart

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heart Transplantation

Share to Homeobox Protein Nkx-2.5

Share to Induced Pluripotent Stem Cells

Share to Myocardial Infarction

Share to Myocytes, Cardiac

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 20558827
DOI: 10.1161/CIRCRESAHA.109.215434
PMCID: PMC2919280

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance.PMID 20558827Read ↗

Human iPSC gene signatures and X chromosome dosage impact response to WNT inhibition and cardiac differentiation fateSemantic proximity Read ↗

Mouse ES cell–derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genesSemantic proximity Read ↗

Isolation and characterization of human embryonic stem cell-derived heart field-specific cardiomyocytes unravels new insights into their transcriptional and electrophysiological profilesSemantic proximity Read ↗

NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populationsSemantic proximity Read ↗

Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem CellsSemantic proximity Read ↗

Molecular and genetic heterogeneity in iPSCs derived from an outbred laboratory mouse populationSemantic proximity Read ↗

Differences between Cellular and Molecular Profiles of Induced Pluripotent Stem Cells Generated from Mouse Embryonic FibroblastsSemantic proximity Read ↗

Natural Cardiogenesis-Based Template Predicts Cardiogenic Potential of Induced Pluripotent Stem Cell LinesSemantic proximity Read ↗

Isolation and characterization of ventricular-like cells derived from NKX2-5 and MLC2v double knock-in human pluripotent stem cellsSemantic proximity Read ↗

Cell Barcoding Reveals Lineage-dependent Outcomes in hiPSC Cardiac DifferentiationSemantic proximity Read ↗

Global transcriptional profiles of beating clusters derived from human induced pluripotent stem cells and embryonic stem cells are highly similarSemantic proximity Read ↗

Large particle fluorescence-activated cell sorting enables high quality single cell RNA-sequencing and functional analysis of adult cardiomyocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.