Article
Common genetic variants associate with serum phosphorus concentration.
Journal of the American Society of Nephrology : JASN - 1 Jul 2010
Kestenbaum Bryan, Glazer Nicole L, Köttgen Anna, Felix Janine F, Hwang Shih-Jen, Liu Yongmei, Lohman Kurt, Kritchevsky Stephen B, Hausman Dorothy B, Petersen Ann-Kristin, Gieger Christian, Ried Janina S, Meitinger Thomas, Strom Tim M, Wichmann H Erich, Campbell Harry, Hayward Caroline, Rudan Igor, de Boer Ian H, Psaty Bruce M, Rice Kenneth M, Chen Yii-Der Ida, Li Man, Arking Dan E, Boerwinkle Eric, Coresh Josef, Yang Qiong, Levy Daniel, van Rooij Frank J A, Dehghan Abbas, Rivadeneira Fernando, Uitterlinden André G, Hofman Albert, van Duijn Cornelia M, Shlipak Michael G, Kao W H Linda, Witteman Jacqueline C M, Siscovick David S, Fox Caroline S
Abstract excerpt
Phosphorus is an essential mineral that maintains cellular energy and mineralizes the skeleton. Because complex actions of ion transporters and regulatory hormones regulate serum phosphorus concentrations, genetic variation may determine interindividual variation in phosphorus metabolism. Here, we report a comprehensive genome-wide association study of serum phosphorus concentration. We evaluated 16,264...
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