Article
Genetic Variants Associated with Circulating Parathyroid Hormone.
Journal of the American Society of Nephrology : JASN - 1 May 2017
Robinson-Cohen Cassianne, Lutsey Pamela L, Kleber Marcus E, Nielson Carrie M, Mitchell Braxton D, Bis Joshua C, Eny Karen M, Portas Laura, Eriksson Joel, Lorentzon Mattias, Koller Daniel L, Milaneschi Yuri, Teumer Alexander, Pilz Stefan, Nethander Maria, Selvin Elizabeth, Tang Weihong, Weng Lu-Chen, Wong Hoi Suen, Lai Dongbing, Peacock Munro, Hannemann Anke, Völker Uwe, Homuth Georg, Nauk Matthias, Murgia Federico, Pattee Jack W, Orwoll Eric, Zmuda Joseph M, Riancho Jose Antonio, Wolf Myles, Williams Frances, Penninx Brenda, Econs Michael J, Ryan Kathleen A, Ohlsson Claes, Paterson Andrew D, Psaty Bruce M, Siscovick David S, Rotter Jerome I, Pirastu Mario, Streeten Elizabeth, März Winfried, Fox Caroline, Coresh Josef, Wallaschofski Henri, Pankow James S, de Boer Ian H, Kestenbaum Bryan
Abstract excerpt
Parathyroid hormone (PTH) is a primary calcium regulatory hormone. Elevated serum PTH concentrations in primary and secondary hyperparathyroidism have been associated with bone disease, hypertension, and in some studies, cardiovascular mortality. Genetic causes of variation in circulating PTH concentrations are incompletely understood. We performed a genome-wide association study of serum PTH concentrations among...
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