Article
The Molecular Basis of Calcium and Phosphorus Inherited Metabolic Disorders.
Genes - 13 May 2021
Papadopoulou Anna, Bountouvi Evangelia, Karachaliou Fotini-Eleni
Abstract excerpt
Calcium (Ca) and Phosphorus (P) hold a leading part in many skeletal and extra-skeletal biological processes. Their tight normal range in serum mirrors their critical role in human well-being. The signalling "voyage" starts at Calcium Sensing Receptor (CaSR) localized on the surface of the parathyroid glands, which captures the "oscillations" of extracellular ionized Ca and transfers the signal downstream....
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