Article
Modeling associations between genetic markers using Bayesian networks.
Bioinformatics (Oxford, England) - 15 Sept 2010
Villanueva Edwin, Maciel Carlos Dias
Abstract excerpt
MOTIVATION: Understanding the patterns of association between polymorphisms at different loci in a population (linkage disequilibrium, LD) is of fundamental importance in various genetic studies. Many coefficients were proposed for measuring the degree of LD, but they provide only a static view of the current LD structure. Generative models (GMs) were proposed to go beyond these measures, giving not only a...
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