Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood.

doi:10.1016/j.jpeds.2010.04.020

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Article

Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood.

The Journal of pediatrics - 1 Oct 2010

Abel Laurent, Plancoulaine Sabine, Jouanguy Emmanuelle, Zhang Shen-Ying, Mahfoufi Nora, Nicolas Nathalie, Sancho-Shimizu Vanessa, Alcaïs Alexandre, Guo Yiqi, Cardon Annabelle, Boucherit Soraya, Obach Dorothée, Clozel Thomas, Lorenzo Lazaro, Amsallem Daniel, Berquin Patrick, Blanc Thierry, Bost-Bru Cécile, Chabrier Stéphane, Chabrol Brigitte, Cheuret Emmanuel, Dulac Olivier, Evrard Philippe, Héron Bénédicte, Lazaro Leila, Mancini Josette, Pedespan Jean-Michel, Rivier François, Vallée Louis, Lebon Pierre, Rozenberg Flore, Casanova Jean-Laurent, Tardieu Marc

Abstract excerpt

OBJECTIVE: To test the hypothesis that predisposition to childhood herpes simplex virus (HSV) type 1 encephalitis (HSE) may be determined in part by human genetic factors. STUDY DESIGN: A genetic epidemiologic survey of childhood HSE (onset at age 3 months to 15 years) over a 20-year period (1985-2004) was conducted throughout France (comprising 29 university hospital neuropediatric centers). A total of 85...

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PMID: 20553844
DOI: 10.1016/j.jpeds.2010.04.020

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