Article
Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.
PloS one - 1 Jan 2016
Abdelmagid Nada, Bereczky-Veress Biborka, Atanur Santosh, Musilová Alena, Zídek Václav, Saba Laura, Warnecke Andreas, Khademi Mohsen, Studahl Marie, Aurelius Elisabeth, Hjalmarsson Anders, Garcia-Diaz Ana, Denis Cécile V, Bergström Tomas, Sköldenberg Birgit, Kockum Ingrid, Aitman Timothy, Hübner Norbert, Olsson Tomas, Pravenec Michal, Diez Margarita
Abstract excerpt
Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain. Although viral latency in neurons is very common in the population, it remains unclear why certain individuals develop HSE. Here we explore potential host genetic variants predisposing to HSE. In order to investigate this we used a rat HSE model comparing the HSE...
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