Article
Evidence for a recessive major gene predisposing to human herpesvirus 8 (HHV-8) infection in a population in which HHV-8 is endemic.
The Journal of infectious diseases - 15 Jun 2003
Plancoulaine Sabine, Gessain Antoine, van Beveren Monique, Tortevoye Patricia, Abel Laurent
Abstract excerpt
Infection by human herpesvirus 8 (HHV-8), as measured by the presence of specific antibodies, was shown in countries in which HHV-8 infection is endemic to exhibit familial aggregation and a peculiar variation with age (rapid increase until puberty followed by a plateau in young adults). To investigate whether host genetic factors could explain these findings, a segregation analysis was performed of 81 families...
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