Article
A major locus on chromosome 3p22 conferring predisposition to human herpesvirus 8 infection.
European journal of human genetics : EJHG - 1 Jun 2012
Pedergnana Vincent, Gessain Antoine, Tortevoye Patricia, Byun Minji, Bacq-Daian Delphine, Boland Anne, Casanova Jean-Laurent, Abel Laurent, Plancoulaine Sabine
Abstract excerpt
Infection with human herpesvirus 8 (HHV-8), the etiological agent of Kaposi's sarcoma, has been shown to display strong familial aggregation, in countries in which HHV-8 infection is endemic. We investigated 40 large families (608 subjects aged one to 88 years) living in an isolated area of Cameroon in which HHV-8 is highly endemic. We performed a two-step genetic analysis for HHV-8 infection status...
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