Article
Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission.
Aging cell - 1 Aug 2010
Palermo Vanessa, Falcone Claudio, Calvani Menotti, Mazzoni Cristina
Abstract excerpt
In this work we report that carnitines, in particular acetyl-l-carnitine (ALC), are able to prolong the chronological aging of yeast cells during the stationary phase. Lifespan extension is significantly reduced in yca1 mutants as well in rho(0) strains, suggesting that the protective effects pas...
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