Article
Apoptosis and aging in mitochondrial morphology mutants of S. cerevisiae.
Folia microbiologica - 1 Jan 2007
Palermo V, Falcone C, Mazzoni C
Abstract excerpt
Cell viability during chronological aging and after apoptotic stimuli in some yeast mutants with altered mitochondrial morphology was followed; a function for the corresponding genes in the apoptotic process was assessed. MDM30 and DNM1, the genes encoding an F-box protein and the dynamin-related GTPase, respectively, are involved in triggering aging and apoptosis. In contrast, YME1, encoding a subunit of the...
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