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Article

Metabolomics-based systematic prediction of yeast lifespan and its application for semi-rational screening of ageing-related mutants.

Aging cell - 1 Aug 2010

Yoshida Ryo, Tamura Takayuki, Takaoka Chika, Harada Kazuo, Kobayashi Akio, Mukai Yukio, Fukusaki Eiichiro

Abstract excerpt

Metabolomics - the comprehensive analysis of metabolites - was recently used to classify yeast mutants with no overt phenotype using raw data as metabolic fingerprints or footprints. In this study, we demonstrate the estimation of a complicated phenotype, longevity, and semi-rational screening for relevant mutants using metabolic profiles as strain-specific fingerprints. The fingerprints used in our experiments...

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PMID: 20550517
DOI: 10.1111/j.1474-9726.2010.00590.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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