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Article

The transthyretin gene is expressed in Schwann cells of peripheral nerves.

Brain research - 12 Aug 2010

Murakami Tatsufumi, Ohsawa Yutaka, Zhenghua Li, Yamamura Ken-Ichi, Sunada Yoshihide

Abstract excerpt

Transthyretin (TTR) is mainly expressed in the liver and choroid plexus of the brain. The majority of familial amyloidotic polyneuropathy cases are caused by a mutant TTR gene. The origin of the TTR deposited in the peripheral nervous system is unknown. We studied the expression of TTR in the peripheral nerves of normal mice and transgenics bearing the human mutant TTR in a mouse Ttr-null background. Using...

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Source

Identifiers

PMID: 20547140
DOI: 10.1016/j.brainres.2010.06.017

Genes

TTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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