Article
Codon usages of genes on chromosome, and surprisingly, genes in plasmid are primarily affected by strand-specific mutational biases in Lawsonia intracellularis.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Apr 2009
Guo Feng-Biao, Yuan Jian-Bo
Abstract excerpt
In this study, the factors driving genome-wide patterns of codon usages in Lawsonia intracellularis genome are determined. For genes on the chromosome of the bacterium, it is found that the most important source of variation results from strand-specific mutational biases. A lesser trend of variation is attributable to genes that are presumed as horizontally transferred. These putative alien genes are unusually GC...
Topics
- Base Composition
- Base Sequence
- Chromosomes, Bacterial
- Codon
- DNA Replication
- DNA, Bacterial
- Gene Transfer, Horizontal
- Genes, Bacterial
- Genome, Bacterial
- Lawsonia Bacteria