Article
Goblet Cells Are Derived from a <i>FOXJ1</i> -Expressing Progenitor in a Human Airway Epithelium
10 Jun 2010
Abstract excerpt
The overproduction of mucus is a key pathology associated with respiratory diseases, such as asthma and chronic obstructive pulmonary disease. These conditions are characterized by an increase in the number of mucus-producing goblet cells in the airways. We have studied the cellular origins of goblet cells using primary human bronchial epithelial cells (HBECs), which can be differentiated to form a stratified...
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