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Article

Maternal angiotensinogen (AGT) haplotypes, fetal renin (REN) haplotypes and risk of preeclampsia; estimation of gene-gene interaction from family-triad data.

BMC medical genetics - 10 Jun 2010

Vefring Hege K, Wee Line, Jugessur Astanand, Gjessing Håkon K, Nilsen Stein T, Lie Rolv T

Abstract excerpt

BACKGROUND: Preeclampsia is a debilitating disorder affecting approximately 3% of pregnant women in the Western world. Although inconclusive, current evidence suggests that the renin-angiotensin system may be involved in hypertension. Therefore, our objective was to determine whether the genes for placental renin (REN) and maternal angiotensinogen (AGT) interact to influence the risk of preeclampsia. METHODS:...

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Source

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Identifiers

PMID: 20537141
DOI: 10.1186/1471-2350-11-90
PMCID: PMC2901215

Genes

AGT
REN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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