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Article

The Gene Variants of Maternal/Fetal Renin-Angiotensin System in Preeclampsia: A Hybrid Case-Parent/Mother-Control Study.

Scientific reports - 11 Jul 2017

Zhang Heng, Li Ying-Xue, Peng Wei-Jun, Li Zhi-Wei, Zhang Chun-Hua, Di Hai-Hong, Shen Xian-Ping, Zhu Jun-Feng, Yan Wei-Rong

Abstract excerpt

Preeclampsia (PE) is a common pregnancy-related complication, and polymorphisms in angiotensinogen (AGT), angiotensin-converting enzyme (ACE), and angiotensin II type 1 receptor (AT1R) are believed to contribute to PE development. We implemented a hybrid study to investigate the influence of maternal and fetal ACE I/D, ACE G2350A, AGT M235T, AGT T174M, and AT1R A1166C polymorphisms on PE in Han Chinese women....

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Identifiers

PMID: 28698595
DOI: 10.1038/s41598-017-05411-z
PMCID: PMC5506018

Genes

ACE
AGT

Variants

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