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Article

Haplotypes of the angiotensin II receptor genes AGTR1 and AGTR2 in women with normotensive pregnancy and women with preeclampsia.

Human mutation - 1 Jul 2004

Plummer Sally, Tower Clare, Alonso Pedro, Morgan Linda, Baker Phil, Broughton-Pipkin Fiona, Kalsheker Noor

Abstract excerpt

Angiotensin II (AII) acts as a growth factor in local systems, mediating diverse effects such as cellular proliferation and apoptosis. These effects are controlled through two main receptor subtypes: AGTR1 and AGTR2. We studied the haplotype frequencies of both receptor genes in women with preeclamptic pregnancies and normotensive pregnant women. We also looked for any association between AGTR1 genotype at sites...

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Source

Identifiers

PMID: 15221785
DOI: 10.1002/humu.20050

Genes

AGTR1
AGTR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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