Article
Serotonin controls the maturation of the GABA phenotype in the ventral spinal cord via 5-HT1b receptors.
Annals of the New York Academy of Sciences - 1 Jun 2010
Allain Anne-Emilie, Ségu Louis, Meyrand Pierre, Branchereau Pascal
Abstract excerpt
Serotonin (5-hydroxytryptamine or 5-HT) is a pleiotropic neurotransmitter known to play a crucial modulating role during the construction of brain circuits. Descending bulbo-spinal 5-HT fibers, coming from the caudal medullary cell groups of the raphe nuclei, progressively invade the mouse spinal cord and arrive at lumbar segments at E15.5 when the number of ventral GABA immunoreactive (GABA-ir) interneurons...
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