Ventrally located commissural neurons express the GABAergic phenotype in developing rat spinal cord.

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Article

Ventrally located commissural neurons express the GABAergic phenotype in developing rat spinal cord.

The Journal of comparative neurology - 28 Jun 1999

Phelps P E, Alijani A, Tran T S

Abstract excerpt

Early-forming commissural neurons are studied intensively as a model of axonal outgrowth and pathfinding, yet the neurotransmitter phenotype of the majority of these neurons is not known. The present study has determined that a substantial number of commissural neurons express the 65-kDa isoform of glutamic acid decarboxylase (GAD65) as early as embryonic day 12 (E 12). Patterns of GAD65 localization were...

Topics

Animals
Antibodies, Monoclonal
Axons
Cell Adhesion Molecules, Neuronal
Contactin 2
Female
Gene Expression Regulation, Developmental
Glutamate Decarboxylase
Immunohistochemistry
Isoenzymes
Membrane Glycoproteins
Neurons
Phenotype
Pregnancy
Rats
Rats, Sprague-Dawley
Spinal Cord
gamma-Aminobutyric Acid

Source

Open in PubMed

Identifiers

PMID: 10379921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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