Article
Sequential activation of the 5-HT1(A) serotonin receptor and TrkB induces the serotonergic neuronal phenotype.
Molecular and cellular neurosciences - 1 May 2000
Galter D, Unsicker K
Abstract excerpt
Serotonin (5-HT) is an important factor controlling survival, differentiation, and plasticity of neurons in serotonergic target regions of the brain and has been implicated in major psychiatric and autonomic disorders. Relatively little is known, however, of factors controlling differentiation and plasticity of developing and adult 5-HT neurons. We show now that 5-HT, the 5-HT1(A) receptor, brain-derived...
Topics
- Animals
- Biomarkers
- Brain-Derived Neurotrophic Factor
- Carbazoles
- Cells, Cultured
- Enzyme Inhibitors
- Indole Alkaloids
- Neurons
- Phenotype
- Phosphotransferases
- RNA, Messenger
- Raphe Nuclei
- Rats
- Rats, Wistar
- Receptor, trkB
- Receptor, trkC
- Receptors, Serotonin
- Receptors, Serotonin, 5-HT1
