Article
Intravenous cell therapy for acute renal failure with serum amyloid A protein-reprogrammed cells.
American journal of physiology. Renal physiology - 1 Aug 2010
Kelly Katherine J, Kluve-Beckerman Barbara, Zhang Jizhong, Dominguez Jesus H
Abstract excerpt
Serum amyloid A protein (SAA), a prominent component of the acute-phase response, is strongly expressed in developing and repairing kidneys and promotes tubulogenesis. Accordingly, we reprogrammed relatively undifferentiated NRK52E cells with the mouse SAA1.1 gene and transplanted SAA-positive and -negative cells into rats with acute renal failure. We found that SAA-positive cells accelerated renal recovery in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
