Article
Acute renal failure in zebrafish: a novel system to study a complex disease
8 Apr 2005
Abstract excerpt
Acute renal failure (ARF) is characterized by a very high mortality essentially unchanged over the past 40 years. Simple vertebrate models are needed to improve our understanding of ARF and facilitate the development of novel therapies for this clinical syndrome. Here, we demonstrate that gentamicin, a commonly used nephrotoxic antibiotic, causes larval zebrafish to develop ARF characterized by histological and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
