Article
Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.
PLoS genetics - 3 Jun 2010
Naukkarinen Jussi, Surakka Ida, Pietiläinen Kirsi H, Rissanen Aila, Salomaa Veikko, Ripatti Samuli, Yki-Järvinen Hannele, van Duijn Cornelia M, Wichmann H-Erich, Kaprio Jaakko, Taskinen Marja-Riitta, Peltonen Leena
Abstract excerpt
To get beyond the "low-hanging fruits" so far identified by genome-wide association (GWA) studies, new methods must be developed in order to discover the numerous remaining genes that estimates of heritability indicate should be contributing to complex human phenotypes, such as obesity. Here we d...
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