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Article

Evidence for positive selection on the Osteogenin (BMP3) gene in human populations.

PloS one - 4 Jun 2010

Wu Dong-Dong, Jin Wei, Hao Xiao-Dan, Tang Nelson Leung Sang, Zhang Ya-Ping

Abstract excerpt

BACKGROUND: Human skeletal system has evolved rapidly since the dispersal of modern humans from Africa, potentially driven by selection and adaptation. Osteogenin (BMP3) plays an important role in skeletal development and bone osteogenesis as an antagonist of the osteogenic bone morphogenetic proteins, and negatively regulates bone mineral density. METHODOLOGY/PRINCIPAL FINDINGS: Here, we resequenced the BMP3...

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Source

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Identifiers

PMID: 20532035
DOI: 10.1371/journal.pone.0010959
PMCID: PMC2881034

Genes

BMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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