Article
Patterns of ancestry, signatures of natural selection, and genetic association with stature in Western African pygmies.
PLoS genetics - 1 Jan 2012
Jarvis Joseph P, Scheinfeldt Laura B, Soi Sameer, Lambert Charla, Omberg Larsson, Ferwerda Bart, Froment Alain, Bodo Jean-Marie, Beggs William, Hoffman Gabriel, Mezey Jason, Tishkoff Sarah A
Abstract excerpt
African Pygmy groups show a distinctive pattern of phenotypic variation, including short stature, which is thought to reflect past adaptation to a tropical environment. Here, we analyze Illumina 1M SNP array data in three Western Pygmy populations from Cameroon and three neighboring Bantu-speaking agricultural populations with whom they have admixed. We infer genome-wide ancestry, scan for signals of positive...
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