Article
Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype.
British journal of cancer - 8 Jun 2010
Kristiansen G, Rose M, Geisler C, Fritzsche F R, Gerhardt J, Lüke C, Ladhoff A-M, Knüchel R, Dietel M, Moch H, Varga Z, Theurillat J-P, Gorr T A, Dahl E
Abstract excerpt
BACKGROUND: We aimed to clarify the incidence and the clinicopathological value of non-muscle myoglobin (Mb) in a large cohort of non-invasive and invasive breast cancer cases. METHODS: Matched pairs of breast tissues from 10 patients plus 17 breast cell lines were screened by quantitative PCR for Mb mRNA. In addition, 917 invasive and 155 non-invasive breast cancer cases were analysed by immunohistochemistry for...
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