Article
Typical medullary breast carcinomas have a basal/myoepithelial phenotype.
The Journal of pathology - 1 Nov 2005
Jacquemier Jocelyne, Padovani Laetitia, Rabayrol Laetitia, Lakhani Sunil R, Penault-Llorca Frédérique, Denoux Yves, Fiche Maryse, Figueiro Paulo, Maisongrosse Véronique, Ledoussal Viviane, Martinez Penuela Jose, Udvarhely Nora, El Makdissi George, Ginestier Christophe, Geneix Jeannine, Charafe-Jauffret Emmanuelle, Xerri Luc, Eisinger François, Birnbaum Daniel, Sobol Hagay
Abstract excerpt
Medullary breast cancer (MBC) is a rare, diagnostically difficult, pathological subtype. Despite being high grade, it has a good prognosis. MBC patients have an excess of BRCA1 germ-line mutation and reliable identification of MBC could help to identify patients at risk of carrying germline BRCA1 mutations or in whom chemotherapy could be avoided. The aim of this study was therefore to improve diagnosis by...
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