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Article

The Difficulty of Targeting Cancer Stem Cell Niches

9 Jun 2010

Abstract excerpt

Normal stem cell niches typically are identified by their distinctive anatomical features and by association with tissue-specific stem cells. Identifying cancer stem cell (CSC) niches presents a special problem because there are few if any common anatomical features among tumors, and the physical phenotypes that reportedly describe the CSCs as entities may be subject to the host's microenvironment, sex, and tumor...

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PMID: 20530700
DOI: 10.1158/1078-0432.ccr-09-2933

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