Article
Zonadhesin Is Essential for Species Specificity of Sperm Adhesion to the Egg Zona Pellucida
8 Jun 2010
Abstract excerpt
Interaction of rapidly evolving molecules imparts species specificity to sperm-egg recognition in marine invertebrates, but it is unclear whether comparable interactions occur during fertilization in any vertebrate species. In mammals, the sperm acrosomal protein zonadhesin is a rapidly evolving molecule with species-specific binding activity for the egg zona pellucida (ZP). Here we show using null mice produced...
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