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Article

Mycobacterial MazG is a novel NTP pyrophosphohydrolase involved in oxidative stress response.

The Journal of biological chemistry - 3 Sept 2010

Lu Liang-dong, Sun Qing, Fan Xiao-yong, Zhong Yi, Yao Yu-feng, Zhao Guo-Ping

Abstract excerpt

MazG nucleoside triphosphate pyrophosphohydrolase (NTP-PPase, EC 3.6.1.8) from the avirulent Mycobacterium tuberculosis H37Ra contains a spontaneous mutation on a highly conserved residue, resulting in an A219E substitution (MtMazG[A219E]). In this work, we show that mycobacterial MazG from either the virulent M. tuberculosis H37Rv (MtMazG) or the fast-growing Mycobacterium smegmatis (MsMazG) is a potent...

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Identifiers

PMID: 20529853
DOI: 10.1074/jbc.M109.088872
PMCID: PMC2934672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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