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Article

A latent cardiomyocyte regeneration potential in human heart disease

2023-09-17

Abstract excerpt

Cardiomyocytes in the adult human heart show a regenerative capacity, with an annual renewal rate around 0.5%. Whether this regenerative capacity of human cardiomyocytes is employed in heart failure has been controversial. Using retrospective 14 C birth dating we analyzed cardiomyocyte renewal in patients with end-stage heart failure. We show that cardiomyocyte generation is minimal in end-stage heart failure pat...

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Identifiers and source

Literature Corpus work
61fa52f8-02e1-59d6-adbc-3104ef704f07
DOI
10.1101/2023.09.14.557681
Open publication

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A latent cardiomyocyte regeneration potential in human heart diseaseDOI 10.1101/2023.09.14.557681
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