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Regulation of endogenous cardiomyocyte proliferation: The known unknowns

6 Apr 2023

Abstract excerpt

Myocardial regeneration in patients with cardiac damage is a long-sought goal of clinical medicine. In animal species in which regeneration occurs spontaneously, as well as in neonatal mammals, regeneration occurs through the proliferation of differentiated cardiomyocytes, which re-enter the cell cycle and proliferate. Hence, the reprogramming of the replicative potential of cardiomyocytes is an achievable goal,...

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PMID: 37030487
DOI: 10.1016/j.yjmcc.2023.04.001

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