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Article

Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.

Emerging infectious diseases - 1 May 2015

de Vries Erik, Guo Hongbo, Dai Meiling, Rottier Peter J M, van Kuppeveld Frank J M, de Haan Cornelis A M

Abstract excerpt

In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.

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Identifiers

PMID: 25897518
DOI: 10.3201/eid2105.141927
PMCID: PMC4412238

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