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Article

Global transcriptional programs in peripheral nerve endoneurium and DRG are resistant to the onset of type 1 diabetic neuropathy in Ins2 mice.

PloS one - 26 May 2010

de Preux Charles Anne-Sophie, Verdier Valérie, Zenker Jennifer, Peter Bastian, Médard Jean-Jacques, Kuntzer Thierry, Beckmann Jacques S, Bergmann Sven, Chrast Roman

Abstract excerpt

While the morphological and electrophysiological changes underlying diabetic peripheral neuropathy (DPN) are relatively well described, the involved molecular mechanisms remain poorly understood. In this study, we investigated whether phenotypic changes associated with early DPN are correlated with transcriptional alterations in the neuronal (dorsal root ganglia [DRG]) or the glial (endoneurium) compartments of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20520806
DOI: 10.1371/journal.pone.0010832
PMCID: PMC2877074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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