Genomic polymorphisms within alpha 7 nicotinic acetylcholine receptor and severe sepsis in Chinese Han population.

doi:10.1111/j.1744-313X.2010.00933.x

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Article

Genomic polymorphisms within alpha 7 nicotinic acetylcholine receptor and severe sepsis in Chinese Han population.

International journal of immunogenetics - 1 Oct 2010

Jin Y, Zhang Y, Wang H, Wu S, Chen Q, Cheng B, Xie G, Hu Y, Fang X

Abstract excerpt

Alpha 7 nicotinic acetylcholine receptor, a kind of ligand-gated ion channel mainly expressed in macrophages, plays a crucial role in improving survival in sepsis via suppressing proinflammatory cytokines. The predisposition of genomic polymorphisms within alpha 7 nicotinic acetylcholine receptor gene (CHRNA7) to sepsis has not been investigated. The current association study was performed to analyse six common...

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Identifiers

PMID: 20518839
DOI: 10.1111/j.1744-313X.2010.00933.x

Genes

CHRNA7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.