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Article

Lack of association between TREM-1 gene polymorphisms and severe sepsis in a Chinese Han population.

Human immunology - 1 Mar 2008

Chen QiXing, Zhou HuiDan, Wu ShuiJing, Wang HaiHong, Lv Chen, Cheng Baoli, Xie GuoHao, Fang XiangMing

Abstract excerpt

Triggering receptor expressed on myeloid cells-1 (TREM-1) is a cell surface receptor expressed on neutrophils and monocytes. TREM-1 acts to amplify inflammation and serves as a critical mediator of inflammatory response in the context of sepsis. Blocking of TREM-1 can protect against sepsis in mice. To date, the predisposition of TREM-1 gene polymorphisms to sepsis has not been reported. This study was designed...

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Identifiers

PMID: 18396215
DOI: 10.1016/j.humimm.2008.01.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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