Article
A non-synonymous SNP in the NOS2 associated with septic shock in patients with sepsis in Chinese populations.
Human genetics - 1 Mar 2013
Wang Zhifu, Feng Kai, Yue Maoxing, Lu Xiaoguang, Zheng Qihan, Zhang Hongxing, Zhai Yun, Li Peiyao, Yu Lixia, Cai Mi, Zhang Xiumei, Kang Xin, Shi Weihai, Xia Xia, Chen Xi, Cao Pengbo, Li Yuanfeng, Chen Huipeng, Ling Yan, Li Yuxia, He Fuchu, Zhou Gangqiao
Abstract excerpt
Sepsis represents a systemic inflammatory response to infection and its sequelae include severe sepsis, septic shock, multiple organ dysfunction syndrome (MODS) and death. Studies in mice and humans indicate that the inducible nitric oxide synthase (iNOS, NOS2) plays an important role in the deve...
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