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Article

Gene variation of the transient receptor potential cation channel, subfamily M, member 2 (TRPM2) and type 2 diabetes mellitus: A case-control study.

Clinica chimica acta; international journal of clinical chemistry - 9 Oct 2010

Romero José R, Germer Soren, Castonguay Amy J, Barton Nathaniel S, Martin Mitchell, Zee Robert Y L

Abstract excerpt

BACKGROUND: Disordered cellular calcium regulation has been implicated in the pathophysiology of diabetes through mechanisms that remain unresolved. The non-selective calcium channel, transient receptor potential cation channel, subfamily M, member 2 (TRPM2), has been recently reported to play a role in insulin secretion by pancreatic beta-cells. We hypothesized that gene variation of TRPM2 may play a role in the...

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Source

Identifiers

PMID: 20515676
DOI: 10.1016/j.cca.2010.05.036

Genes

TRPM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene variation of the transient receptor potential cation channel, subfamily M, member 2 (TRPM2) and type 2 diabetes mellitus: A case-control study.PMID 20515676Read ↗

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