Article
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with coronary artery disease in the Chinese Han population.
Clinical laboratory - 1 Jan 2011
Liu Rui, Zhang Yanjun
Abstract excerpt
BACKGROUND: Recent studies suggest that endocannabinoids modulate food intake, energy balance, and lipid and glucose metabolism through the cannabinoid receptor-1 (CNR1) gene. Treatment of cannabinoid receptor antagonists resulted in an improvement of cardiovascular risk factors including obesity, glucose tolerance, dyslipidemia, and measures of inflammation. G1359A polymorphism of the CNR1 may be associated with...
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