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Article

Lon protease quality control of presecretory proteins in Escherichia coli and its dependence on the SecB and DnaJ (Hsp40) chaperones.

The Journal of biological chemistry - 23 Jul 2010

Sakr Samer, Cirinesi Anne-Marie, Ullers Ronald S, Schwager Françoise, Georgopoulos Costa, Genevaux Pierre

Abstract excerpt

Various environmental insults result in irreversible damage to proteins and protein complexes. To cope, cells have evolved dedicated protein quality control mechanisms involving molecular chaperones and proteases. Here, we provide both genetic and biochemical evidence that the Lon protease and the SecB and DnaJ/Hsp40 chaperones are involved in the quality control of presecretory proteins in Escherichia coli. We...

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Identifiers

PMID: 20504766
DOI: 10.1074/jbc.M110.133058
PMCID: PMC2906341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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