Article
Trigger Factor can antagonize both SecB and DnaK/DnaJ chaperone functions in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America - 27 Feb 2007
Ullers Ronald S, Ang Debbie, Schwager Françoise, Georgopoulos Costa, Genevaux Pierre
Abstract excerpt
Polypeptides emerging from the ribosome are assisted by a pool of molecular chaperones and targeting factors, which enable them to efficiently partition as cytoplasmic, integral membrane, or exported proteins. In Escherichia coli, the chaperones SecB, Trigger Factor (TF), and DnaK are key players in this process. Here, we report that, as with dnaK or dnaJ mutants, a secB null strain exhibits a strong...
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