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Article

CYP17 polymorphisms and prostate cancer outcomes.

The Prostate - 1 Jul 2010

Wright Jonathan L, Kwon Erika M, Lin Daniel W, Kolb Suzanne, Koopmeiners Joseph S, Feng Ziding, Ostrander Elaine A, Stanford Janet L

Abstract excerpt

OBJECTIVE: Cytochrome P450 17alpha-hydroxylases-C-(17,20)-lyase (CYP17) is a key enzyme involved with the androgen biosynthesis pathway and has recently been targeted for therapy in men with advanced prostate cancer (PCa). However, studies relating prostate cancer outcomes with CYP17 gene variants have conflicting results. In this study we analyzed Single Nucleotide Polymorphisms (SNPs) spanning the CYP17 gene...

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Identifiers

PMID: 20503394
DOI: 10.1002/pros.21143
PMCID: PMC2878282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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