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Article

Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2010

Smith Andrew J, Lippiat Jonathan D

Abstract excerpt

The family of CLC proteins comprises both Cl(-) channels and Cl(-)/H(+) exchange transporters with varying degrees of voltage dependence. The human CLC-5 is an electrogenic voltage-dependent 2Cl(-)/1H(+) exchanger that gives rise to strongly outwardly rectifying currents when expressed. We conduc...

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Identifiers

PMID: 20501796
DOI: 10.1096/fj.09-150649
PMCID: PMC2996913

Genes

CLC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20501796-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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