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Article

Differential adipokine response in genetically predisposed lean and obese rats during inflammation: a role in modulating experimental colitis?

American journal of physiology. Gastrointestinal and liver physiology - 1 Nov 2009

Hyland Niall P, Chambers Adam P, Keenan Catherine M, Pittman Quentin J, Sharkey Keith A

Abstract excerpt

The relationship between a predisposition to obesity and the development of colitis is not well understood. Our aim was to characterize the adipokine response and the extent of colitis in diet-induced obese (DIO) rats. DIO and control, diet-resistant (DR) animals were administered either saline or trinitrobenzene sulfonic acid (TNBS) to induce colitis. Macroscopic damage scores and myeloperoxidase (MPO) activity...

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PMID: 20501435
DOI: 10.1152/ajpgi.00164.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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