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Article

Altered inflammatory gene expression underlies increased susceptibility to murine postoperative ileus with advancing age.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jun 2007

Moore Beverley A, Albers Kathryn M, Davis Brian M, Grandis Jennifer R, Tögel Sandra, Bauer Anthony J

Abstract excerpt

Susceptibility to postoperative ileus following abdominal surgery increases with advancing age. The mechanisms underlying this phenomenon are unknown. This study compares functional and molecular endpoints between young-adult (2 mo old), middle-aged (15 mo old), and elderly mice (26-30 mo old) to identify potential mechanisms. Susceptibility to ileus was assessed by measuring gastrointestinal transit (geometric...

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Identifiers

PMID: 17363464
DOI: 10.1152/ajpgi.00570.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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