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Article

Maternal high‐fat diet consumption enhances offspring susceptibility to DSS‐induced colitis in mice

24 Mar 2017

Abstract excerpt

OBJECTIVE: Maternal high-fat diet (HFD) may alter the offspring intestinal immune system, thereby enhancing susceptibility toward inflammatory bowel disease. The objective of the current study was to investigate the impact of maternal HFD on offspring intestinal health using a mouse model of dextran sulfate sodium (DSS)-induced colitis. METHODS: Dams were provided with either HFD (60%) or control diet. After...

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PMID: 28339172
DOI: 10.1002/oby.21816

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